2022
Weaver SD, Schuster-Little N, Whelan RJ. Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics. Analytical Methods, 2022, 14, 1103-1110. DOI: 10.1039/D1AY02145A
Sherman, L. M.; Finley, M. D.; Borsari, R. K.; Schuster-Little, N; Strausser, S. L.; Whelan, R. J.; Jenkins, D. M.; Camden, J. P., N-Heterocyclic Carbene Ligand Stability on Gold Nanoparticles in Biological Media. ACS Omega, (2022), 7(1), 1444–1451. DOI: 10.1021/acsomega.1c06168
2021
Mace C, Morrin A, Whelan RJ. "Introduction to bioanalytical sensors for real-world applications." Anal Methods, 2021, 13, 1776-1777.
Weaver SD and Whelan RJ. "Characterization of DNA aptamer–protein binding using fluorescence anisotropy assays in low-volume, high-efficiency plates." Anal Methods. 2021 Mar 18;13(10):1207-1310.
Schuster-Little N, Fritz-Klaus R, Etzel M, Patankar N, Javeri S, Patankar MS, Whelan RJ. "Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites." Analyst. 2021 Jan 4;146(1):85-94. doi: 10.1039/d0an01701a. PMID: 33141132; PMCID: PMC7785687.
COVER PAGE LINK
COVER PAGE LINK
2020
Schuster-Little N, Madera S, Whelan R. "Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) using suspension trapping (STrap)." Anal Bioanal. Chem. 2020, 412(24), 6361-6370.
Garvin, M.C., Schijf, J., Kaufman, S.R., Konow, C., Liang, D., Nigra, A.E., Stracker, N.H., Whelan, R.J., Wiles, G.C. "A survey of trace metal burdens in increment cores from eastern cottonwood (Populus deltoides) across a childhood cancer cluster, Sandusky County, OH, USA." Chemosphere, 2020,238,124528.
Garvin, M.C., Schijf, J., Kaufman, S.R., Konow, C., Liang, D., Nigra, A.E., Stracker, N.H., Whelan, R.J., Wiles, G.C. "A survey of trace metal burdens in increment cores from eastern cottonwood (Populus deltoides) across a childhood cancer cluster, Sandusky County, OH, USA." Chemosphere, 2020,238,124528.
2018
Mears, K.S., Markus, D.L., Ogunjimi, O., Whelan, R.J. “Experimental and mathematical evidence that thrombin-binding aptamers form a 1 aptamer: 2 protein complex,” Aptamers, 2018, 2, 64-73.
Garvin, M.C., Austin, A., Boyer, K., Gefke, M., Wright, C., Pryor, Y., Soble, A., Whelan, R.J. “Attraction of Culex pipiens to house sparrows is influenced by host age but not uropygial gland secretions,” Insects, 2018, 9, 127.
Alharbi, Y, Patankar, M.S., and Whelan, R.J. “Antibody based therapy for ovarian cancer,” In Ovarian Cancer Immunotherapy: Current Perspectives; Farghaly, S., Ed.; Oxford University Press: Oxford, 2018. (invited)
Garvin, M.C., Austin, A.L, Stracker, N.H., Slowinski, S.P. Rutter, J.E., Butler, M., Michel, M., Whelan, R.J. “Attraction of Culex pipiens to uropygial gland secretions does not explain feeding preference for American robins,” J. Vector Ecol. 2018, 43, 110-116.
2017
Pires, T.A., Narovec, C.M., Whelan, R.J. “Effects of cationic proteins on gold nanoparticle/aptamer assays,” ACS Omega 2017, 2, 8222-8226.
Scoville, D.J., Uhm, T.K.B., Shallcross, J.A., Whelan, R.J. “Selection of DNA aptamers for ovarian cancer biomarker CA125 using One-Pot SELEX and high-throughput sequencing,” J. Nucl. Acids 2017, Article ID 9879135, 9 pages, 2017. doi:10.1155/2017/9879135.
2016
Kapur, A., Felder, M., Fass, L., Kaur, J., Czarnecki, A., Rathi, K., Zeng, S., Osowski, K.K. Howell, C., Xiong, M.P., Whelan, R.J., Patankar, M.S. “Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation,” Sci. Rep. 2016, 6, 27530
2010-2015
Eaton, R.M., Shallcross, J.A., Mael, L.E., Mears, K.S., Minkoff, L., Scoville, D.J., Whelan, R.J. “Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing,” Anal. Bioanal. Chem. 2015, 407, 6965-6973.
Felder, M., Kapur, A., Gonzalez-Bosquet, J., Horibata, S., Heintz, J., Albrecht, R., Faas, L., Kaur, J., Hu, K., Shojaei, H., Whelan, R.J., Patankar, M.S. “MUC16 (CA125): Tumor biomarker to cancer therapy, a work in progress,” Molecular Cancer 2014, 13, 129. (A “highly accessed” article, with >35,400 views as of 8/2018)
Liu, Y., Whelan, R.J., Pattnaik, B.R., Ludwig, K., Subudhi, E., Rowland, H., Claussen, N., Zucker, N., Uppal, S., Kushner, D.M., Felder, M., Patankar, M.S., and Kapur, A. “Terpenoids from Zingiber officinale (Ginger) Induce Apoptosis in Endometrial Cancer Cells through the Activation of p53,” PLoS ONE 2012, 7 (12): e53178.
Shaw, C.L., Rutter, J.E., Austin, A.L., Garvin, M.C., and Whelan, R.J. “Volatile and Semivolatile Compounds in Gray Catbird Uropygial Secretions Vary with Age and between Breeding and Wintering Grounds,” J. Chem. Ecol. 2011, 37, 329-339. (This article was featured on the cover of the April 2011 issue)
COVER PAGE LINK
COVER PAGE LINK
Berman, Z.T., Moore, L.J., Knudson, K.E., and Whelan, R.J. “Synthesis and Structural Characterization of the Peptide Epitope of the Ovarian Cancer Biomarker CA125 (MUC16),” Tumor Biol. 2010, 31, 495-502.
Whelan, R.J., Levin, T.C., Owen, J.C., and Garvin, M.C. “Short-chain Carboxylic Acids from Gray Catbird (Dumetella carolinensis) Uropygial Secretions Vary with Testosterone Levels and Photoperiod,” Comp. Biochem. Physiol. B, 2010, 156, 183-188.
Post Doc-University of Michigan
Yang, P., Whelan, R.J., Mao, Y., Lee, A. W.-M., Carter-Su, C., and Kennedy, R.T. “Multiplexed Detection of Protein-Peptide Interaction and Inhibition Using Capillary Electrophoresis,” Anal. Chem. 2007, 79, 1690-1695.
Yang, P., Whelan, R.J., Jameson, E.E., Kurzer, J.H., Argetsinger, L.S., Carter-Su, C., Kabir, A., Malik, M., and Kennedy, R.T. “Capillary Electrophoresis and Fluorescence Anisotropy for Quantitative Analysis of Rapid Peptide-Protein Interactions using JAK2 and SH2-Bβ as a Model System,” Anal. Chem. 2005, 77, 2482-2489.
Whelan, R.J., Sunahara, R.K., Neubig, R.R., and Kennedy, R.T. “Affinity Assays using Fluorescence Anisotropy with Capillary Electrophoresis Separation,” Anal. Chem. 2004, 76, 7380-7386.
Graduate School-Stanford University
Wheeler, A.R., Chah, S., Whelan, R.J., and Zare, R.N. “Poly(dimethylsiloxane) Microfluidic Flow Cells for Surface Plasmon Resonance Spectroscopy,” Sens. Actuat. B 2004, 98, 208-214.
Whelan, R.J. and Zare, R.N. “Single-Cell Immunosensors for Protein Detection,” Biosens. Bioelectron. 2003, 19, 331-336.
Wheeler, A.R., Throndset, W.R., Whelan, R.J., Leach, A.M. Zare, R.N., Liao, Y.H., Farrell, K., Manger, I.D., and Daridon, A. “Microfluidic Device for Single Cell Analysis,” Anal. Chem. 2003, 75, 3249-3254.
Whelan, R.J. and Zare, R.N. “Surface Plasmon Resonance Detection for Capillary Electrophoresis Separations,” Anal. Chem. 2003, 75, 1542-1547.
Whelan, R.J., Wohland, T., Neumann, L., Huang, B., Kobilka, B.K, and Zare, R.N. “Analyzing Biomolecular Interactions Using a Miniaturized Surface Plasmon Resonance Sensor,” Anal. Chem. 2002, 74, 4570-4576.
Neumann, L., Wohland, T., Whelan, R.J., Zare, R.N., Kobilka, B.K. “Functional Immobilization of a Ligand-Activated G Protein Coupled Receptor,” ChemBioChem. 2002, 3, 993-998.
Teaching Publications
Ricker, A.S. and Whelan, R.J. “Reading, Writing, and Peer Review: Engaging With Chemical Literature in a 200-Level Analytical Chemistry Course,” in Integrating Information Literacy into the Chemistry Curriculum. Editors: C.F. Lovit, K. Shuyler, Y.Li. ACS Symposium Series Vol. 1232, 2016.
Noroski, J. and Whelan, R.J. Instructor Solutions Manual for Chemistry: Principles, Patterns, and Applications; Benjamin Cummings: San Francisco, 2007.
Whelan, R.J., Hannon, T.E., Rakestraw, D.J., and Zare, R.N. “Application of Ion Chromatography to the Investigation of Real-World Samples,” J. Chem. Educ. 2004, 81, 1299-1302.
Whelan, R.J. and Zare, R.N. “Teaching Effective Communication in a Writing-Intensive Analytical Chemistry Course,” J. Chem. Educ. 2003, 80, 904-906.
