Welcome to the Whelan Lab!
We are a bioanalytical chemistry lab studying Ovarian Cancer.
Our Motivation:
The long-term survival statistics associated with ovarian cancer have remained unchanged for decades, and most ovarian cancer patients are diagnosed only after their disease has progressed to a metastatic stage. These cancer deaths are largely preventable: early detection of ovarian cancer correlates strongly with high rates of long-term survival. Early detection of ovarian cancer remains out of reach, however, in part because the existing tests for cancer-specific proteins (biomarkers) are insufficiently informative to be useful.
We view ovarian cancer as a human health problem in need of a measurement science solution. If we can identify alternative affinity probes—displaying more reliable detection of cancer-associated proteins—we can then use these probes as the basis of new tests for ovarian cancer.
Our Motivation:
The long-term survival statistics associated with ovarian cancer have remained unchanged for decades, and most ovarian cancer patients are diagnosed only after their disease has progressed to a metastatic stage. These cancer deaths are largely preventable: early detection of ovarian cancer correlates strongly with high rates of long-term survival. Early detection of ovarian cancer remains out of reach, however, in part because the existing tests for cancer-specific proteins (biomarkers) are insufficiently informative to be useful.
We view ovarian cancer as a human health problem in need of a measurement science solution. If we can identify alternative affinity probes—displaying more reliable detection of cancer-associated proteins—we can then use these probes as the basis of new tests for ovarian cancer.
June 2021: Whelan Lab Matching Shirts!
Announcements
It's official- a Third Cover for the Whelan Lab!
Naviya and Simon's recent publication, "Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics", has scored the cover for issue 11 of Analytical Methods this year!
March 22, 2022 Analyst Reviewer Commendation for 2021.Dr. Whelan has been named an outstanding reviewer for Analyst. This is the second year in a row that she has earned this honor. A hearty congratulations to our fearless leader!
February 24, 2022 |
A 2022 Publication!Congratulations to Simon and Naviya for their first Whelan Lab publication of 2022, entitled "Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics."
Great Job to all!! February 12, 2022 New Funding from the Center for Bioanalytic Metrology!The Whelan Lab is proud to announce that the CBM has chosen to fund our work to develop new methods to detect D-amino acid-containing peptides. We are excited for the opportunity to advance this research!
November 15, 2021 |
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Whelan Lab Funding -Center for Bioanalytic Metrology (an NSF-IUCRC) -T.E.A.L. Foundation -Institute for Precision Health -Indiana CTSI Disease Diagnostics Inventors Challenge -Walther Cancer Foundation -CBBI (to Naviya and Simon) -Berry Family Foundation Fellowship -Rebecca Taiclet Hizer Memorial Fellowship -Harper Cancer Research Institute |
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